http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2327544-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0827 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 |
| filingDate | 2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25dcbbc3ba6c1827a4d364e7427cf734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e5fbacd60d83aa94dec9fdc24a50f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f9aa5e2571a34c15807b10a2a4ea178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec0ead050cf5db694ce5ae0f295853e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54fffa6af0c3c4d8d70c6365083612a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4a979893eb17109c1ea051588066f7f |
| publicationDate | 2009-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2327544-T3 |
| titleOfInvention | NEW COMPOUNDS AS INHIBITORS OF SERINA PROTEASA NS3 DE VIRUS DE HEPETITIS C. |
| abstract | A compound, or enantiomers, stereoisomers, rotamers, tautomers or racemates of said compound, or a pharmaceutically acceptable salt, solvate or ester of said compound, wherein said compound has the general structure shown in Formula I: ** see formula ** in which: R 1 is H, OR 8, NR 9 R 10 or CHR 9 R 10, where R 8, R 9 and R 10 can be the same or different, each independently selected from the group consisting of H, alkyl- , alkenyl-, alkynyl-, aryl-, heteroalkyl-, heteroaryl-, cycloalkyl-, heterocyclyl-, arylalkyl- and heteroarylalkyl; A and M may be the same or different, each independently being selected from R, OR, NHR, NRR '', SR, SO2R and halo; or A and M are connected to each other so that the rest: ** see formula ** shown above in Formula I forms a three, four, six, seven or eight membered cycloalkyl, a four to eight membered heterocyclyl, a six to ten member aryl or a five to ten member heteroaryl; E is C (H) or C (R); L is C (H), C (R), CH2C (R) or C (R) CH2; R, R '', R 2, and R 3 may be the same or different, each independently being selected from the group consisting of H, alkyl-, alkenyl-, alkynyl-, cycloalkyl-, heteroalkyl-, heterocyclyl-, aryl- , heteroaryl-, (cycloalkyl) alkyl-, (heterocyclyl) alkyl-, aryl-alkyl- and heteroaryl-alkyl-; or alternatively R and R "in NRR" are connected to each other such that NRR "forms a four to eight membered heterocyclyl; and Y is selected from the following residues: ** see formula ** where G is NH or O; and R 15 R 16, R 17 R 18, and R 19 may be the same or different, each independently being selected from the group consisting of H, alkyl, heteroalkyl, alkenyl, heteroalkenyl, alkynyl, heteroalkynyl, cycloalkyl, heterocyclyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl, or alternatively, (i) R 15 and R 16 are connected to each other to form a four to eight member cyclic structure, or R 15 and R 19 are connected to each other to form a cyclic four structure to eight members, and (ii) similarly; independently, R 17 and R 18 connect to each other to form a three to eight membered cycloalkyl or heterocyclyl; wherein each of said alkyl, aryl, heteroaryl, cycloalkyl or heterocyclyl may be unsubstituted or optionally substituted independently with one or more moieties selected from the group consisting of: hydroxy, alkoxy, aryloxy, thio, alkylthio, arylthio, amino, amido , alkylamino, arylamino, alkylsulfonyl, arylsulfonyl, sulfonamido, alkylsulfonamido, arylsulfonamido, alkyl, aryl, heteroaryl, keto, carboxy, carbalkoxy, carboxamido, alkoxycarbonylamino, alkoxycarbonyloxy, alkylureido, arylureido, halo, cyano and nitro. |
| priorityDate | 2004-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.