http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2326980-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C04B35-632 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 |
| filingDate | 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9012efdb5a5d14a72969ab6e82806bd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7135b43f54db5fc5058d838eac38cd43 |
| publicationDate | 2009-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2326980-T3 |
| titleOfInvention | USEFUL AMINOBENZIMIDAZOLES AS SELECTIVE ANTAGONISTS OF THE RECEIVER OF THE CONCENTRATED HORMONE OF MELAMINE (MCH) FOR THE TREATMENT OF OBESITY AND ASSOCIATED DISORDERS. |
| abstract | A compound represented by the structural formula ** see formula ** or one of its pharmaceutically acceptable salts or solvates, where the dashed line in ** see formula ** represents (i) an optional bond that may be present or absent, and if is present, forms a double bond with the adjacent single bond, or (ii) -C (R 5 R 8) -, -C (R 5 R 8) -C (R 5 R 8) - or -C (R 11 R 12); m is 1, 2, 3 or 4; n is 0, 1 or 2; p is 0, 1 or 2; Ar is aryl, heteroaryl, aryl substituted with R 4 or heteroaryl substituted with R 4; Z is -NR 5 R 6, -NR 5 C (O) R 3, -C (O) NR 5 R 6, -NR 5 C (O) NR 5 R 6, -NR 5 C (O) OR 3, -NR 5 S (O2) R 3, -S (O2) NR 5 R 6, -S (O2) R 3, -C (O) R 3, -C (O) OR 6, -OH, alkoxy, * * see formula ** or ** see formula ** R 1 is 1 to four radicals, each R 1 is independently selected from the group consisting of hydrogen, -OH, halogen, alkyl, alkoxy, -OCF3, -CF3 or -CN , or two R1 radicals in adjacent carbons of the ring can be joined together to form a methylenedioxy or ethylenedioxy group; R 2 is hydrogen, alkyl, alkyl substituted with R 10, cycloalkyl, cycloalkyl substituted with R 10, aralkyl, heterocyclyl, -C (O) R 3, -S (O2) R 3 or -C (O) NR 5 R 6 ; R 3 is alkyl, aryl, aralkyl, heteroaryl, aralkyl substituted with R 4, aryl substituted with R 4 or heteroaryl substituted with R 4; R 4 is 1 to 5 radicals, each R 4 is independently selected from the group consisting of hydrogen, heterocyclyl, heterocyclyl substituted with R 9, heterocyclylalkyl-, heterocyclyl alkyl substituted with R 9, -OH, -alkoxy, -OCF 3, - CN, alkyl, halogen, -NR 5 R 6, -NR 5 C (O) R 7, -C (O) NR 5 R 8, -NR 5 S (O 2) R 7, -S (O 2) NR 5 R 6, -S (O2) R 7, -COR 7, -C (O) OR 5, CF3, - (rent) NR 5 R 6, - (rent) NR 6 C (O) R 7, - ( rent) NR 6 S (O2) R 7, - (rent) -NR 5 C (O) NR 5 R 6, - (rent) NR 5 C (O) OR 7, CHO, -C = (NOR 5) and ** see formula ** R 5 is hydrogen or alkyl; R 6 is hydrogen, alkyl, aryl, aralkyl or heteroaryl; R 7 is alkyl; aryl, aralkyl or heteroaryl; R 8 is hydrogen or alkyl; R 9 is alkyl, -OH or hydroxyalkyl; R 10 is alkoxy, halogen, -C (O) NR 5 R 6, -C (O) OR 6, -NR 5 R 6 or -OH; R 11 is hydrogen or halogen; and R 12 is hydrogen or halogen. |
| priorityDate | 2003-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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