abstract |
Use of a polypeptide comprising a 20 amino acid sequence that has: - at least 50% identity with the sequence SEQ ID NO: 1; - cysteine residues in positions 2, 5, 6, 8, 9, 14, 17 and 18; and the same functional activity as mature hepcidin forms of a vertebrate; or of a nucleic acid encoding said polypeptide, to prepare a medicament to reduce iron overload. |