http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2325265-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-38 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-05 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-38 |
filingDate | 2004-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb54c80355b2505f72019786ff33d94c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92811d9b51023e133a63987647b8a19e |
publicationDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2325265-T3 |
titleOfInvention | PROCEDURE FOR THE PREPARATION OF CPLA2 INHIBITORS. |
abstract | Procedure for the preparation of a compound of formula (I) ** see formula ** in which: n is an integer in the range between 0 and 10; R 1 represents a linear or branched C 1-C 10 alkyl group, or -CH 2-phenyl in which the phenyl optionally has up to two substituents independently selected from the group consisting of C 1 -C 4 alkyl, C 1 -C 4 alkoxy, halogen and nitrile, each alkyl and alkoxy being optionally substituted by one to the maximum number of halogen atoms; R2 and R3 are each independently selected from the group consisting of H, halogen, nitrile, C1-C4 alkyl and C1-C4 alkoxy; and R 4 represents a linear or branched C 1-C 10 alkyl group, ** see formula ** in which R 2a and R 3a are each independently selected from the group consisting of H, halogen, nitrile, C1- alkyl C4 and C1-C4 alkoxy, said process comprising: a) reacting compound R1-SO2Cl with compound HC * C- (CH2) n-NH2 or a salt thereof, in which n represents an integer from 0 to 10, under alkaline conditions to produce an intermediate compound of formula (II) ** see formula ** and then; b) react the compound of formula (II) with the compound of formula ** see formula ** |
priorityDate | 2003-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.