| abstract |
Compounds of the formula I ** see formula ** in which D means phenyl, pyridyl or thienyl substituted once or twice by Hal, R 1 means H, = O, COOR 3, OH, OA, NH2, alkyl with 1, with 2, with 3, with 4, with 5 or with 6 carbon atoms, N3, ethynyl, vinyl, allyloxy, -OCOR 3, NHCOA or NHSO2A, R 2 means H, = O, OH, OA or alkyl with 1, with 2, with 3, with 4, with 5 or with 6 carbon atoms, R 1 and R 2 mean, together also, a carbocycle with 3 to 6 members, bound in a spirocyclic manner, R 3 means H or A, R 4 means H or A, means pyrrolidin-1,2-diyl, piperidin-1,2-diyl, oxazolidin-3,4- or -3,5-diyl, thiazolidin-3,4-diyl, 2,5-dihydro- 1H-pyrrol-1,5-diyl, [1,3] -dioxolan-4,5-diyl, [1,3] -oxazinan-3,4-diyl, piperazin-1,4-diyl, tetrahydrofuran-3, 4-diyl or azetidin-1,2-diyl, G means (CH 2) not (CH 2) nNH-, X means CONH, Y means 1,3-phenylene or unsubstituted 1,3-phenylene or substituted one or two times for methyl, for trifluoromethyl, for et ilo, by propyl, by Cl or by F, T means morpholin-4-yl substituted once or twice by carbonyl oxygen, A means alkyl with 1 to 10 unbranched or branched carbon atoms and in which they can be replaced from 1 to 7 atoms of H by F, Hal means F, Cl, Br or I, n means 0, 1 or 2, as well as their solvates, their salts and their stereoisomers, pharmaceutically employable, including their mixtures in all proportions . |