| abstract |
Compounds of the general formula ** see formula ** in which R1 is the group ** see formula ** R 2 is a non-aromatic heterocycle, the term "non-aromatic heterocycle" denotes a five or six membered heterocyclic ring, containing one or two heteroatoms, chosen from the group consisting of O, N or S, or is OR '' or N (R '' '') 2; R '' is C1-C7 alkyl, C1-C7 alkyl substituted by halogen or - (CH2) n-cycloalkyl; R '' '' is C 1 -C 7 alkyl; R 3 is NO2, CN or SO2R ''; R 4 is hydrogen, hydroxy, halogen, NO 2, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, C 1 -C 7 alkoxy, SO 2 R '' or C (O) OR '' ''; R 5 / R 6 / R 7 are hydrogen, halogen, C 1 -C 7 alkyl or C 1-C 7 alkyl substituted by halogen; X 1 / X 1 '' are CH or N, with the proviso that X 1 / X 1 '' are not simultaneously CH; X 2 is O, S, NH or N (C 1 -C 7 alkyl); n is 0, 1 or 2; and to pharmaceutically active acid addition salts. |