http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2324128-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_213e7b98bce3a9d6be9936049694fa1a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-902 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7e44ce9b8353ebef26d333f1e1ba29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_febf7a97d585ef4301f4a22798dfce76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bcbe99cb4c08f0426434510c9fca26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b93c0cfc1e360065cd854aa533427c0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc046cd2b521447574cc1d4eef239624 |
| publicationDate | 2009-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2324128-A1 |
| titleOfInvention | METHOD FOR THE DIAGNOSIS OF HEPATOCELLULAR CARCINOMA THROUGH THE USE OF MOLECULAR MARKERS. |
| abstract | Method for the diagnosis of carcinomanHepatocellular using molecular markers.n n n Using a proteomic approach, hepatocellular carcinoma (HCC) markers in the liver of a knockout mouse ( MAT1A - / - ) have been identified for the MAT1A gene (deficient in the synthesis of S-adenosylmethionine). 27 proteins have been detected whose expression is altered in at least 50% of the tumors analyzed. Among them, 13 proteins have been validated in biopsies of patients with HCC of different etiology, and 7 of them in biopsies of patients with liver cirrhosis, stage prior to the development of HCC, which allows to distinguish between previous stages of the disease and even between different etiologies (viral and alcoholic). Having a panel of markers can help define more precisely the alterations associated with the development of HCC and thereby facilitate the prognosis and diagnosis of this disease. |
| priorityDate | 2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 263.