| abstract |
An aqueous pharmaceutical composition of adenovirus containing a polyol in a defective amount to promote maintenance of adenoviral infectivity, wherein the composition further includes Tween-20 or Tween-80, wherein in the latter case the composition is not a composition that consists of 1 x 10 9 to 1 x 10 3 particles / ml A / C / N 53, 0.5 to 10 mg / ml of monobasic sodium phosphate, 0.5 to 10 mg / ml of tromethamine, 5 to 25 mg / ml of sucrose, 20 to 200 mg / ml of glycerol, 0.1 to 1 mg / ml of magnesium chloride, 0.03 to 0.3 mg / ml of polysorbate 80 and water for injection to reach the total volume. |