abstract |
A liquid pharmaceutical formulation containing nicotine characterized in that nicotine is present as a nicotine base, because it is for administration to the oral cavity, by spray, dropper or pipette, preferably by spraying, most preferably by spraying under the tongue, because it is alkalized by buffering and / or pH regulation in such a way that in administration to a subject the pH of the subject's oral cavity liquid is temporarily increased by 0.3 or 4 pH units. |