http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2322907-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac2c17e532220d91aca9a28ef60f178b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 |
filingDate | 2004-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7e11f0c0dde89c48f7dbafd1e3a392a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7742e171b942068ed1b8424436219136 |
publicationDate | 2009-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2322907-T3 |
titleOfInvention | USEFUL PIPERAZINAS FOR THE TREATMENT OF PAIN. |
abstract | A compound of the formula (I): ** (See formula) ** or a pharmaceutically acceptable salt thereof, characterized in that: Ar1 is ** (See formula) ** Ar2 is ** (See formula) ** R1 is -H, -halo, -CH3, -CN, -NO2, -OCH3, -NH2, -C (halo) 3, -CH (halo) 2, or -CH2 (halo); each R2 is independently: (a) -halo, -OH, -NH2, -CN, or -NO2; (b) - (C1-C10) alkyl, - (C2-C10) alkenyl, - (C2-C10) alkynyl, - (C3-C10) cycloalkyl, - (C8-C14) bicycloalkyl, - (C8-C14) tri -cycloalkyl, - (C5-C8) cycloalkenyl, - (C8-C14) bicycloalkenyl, - (C8-C14) tricycloalkenyl, - (3- to 7-bodies) heterocycle, or - (7- to 10-bodies) bicycloheterocycle, each of which is substituted or not with one or more R5 groups; or (c) -phenyl, -naphthyl, - (C14) aryl or - (5- to 10-bodies) heteroaryl, each of which is substituted or not with one or more R6 groups; each R3 is independently: (a) -halo, -OH, -NH2, -CN, or -NO2; (b) - (C1-C10) alkyl, - (C2-C10) alkenyl, - (C2-C10) alkynyl, - (C3-C10) cycloalkyl, - (C8-C14) bicycloalkyl, - (C8-C14) trici -cycloalkyl, - (C5-C10) cycloalkenyl, - (C8-C14) bicycloalkenyl, (C8-C14) tricycloalkenyl, - (3- to 7-bodies) heterocycle, or - (7- to 10-bodies) bicycloheterocycle, each one of which is substituted or not with one or more R5 groups; or (c) -phenyl, -naphthyl, - (C14) aryl or - (5- to 10-bodies) heteroaryl, each of which is substituted or not with one or more R6 groups; R4 is -H, -CN, -C (O) O (C1-C4) alkyl, O -C (O) NH ((C1-C4) alkyl); each R5 is independently -CN, -OH, - (C1-C6) alkyl, - (C2-C6) alkenyl, - (C2-C6) alkynyl, -halo, -N3, -NO2, -N (R7) 2, -CH = NR7, -NR7OH, -OR7, -COR7, -C (O) OR7, -OC (O) R7, -OC (O) OR7, -SR7, -S (O) R7, or -S (O ) 2R7; each R6 is independently - (C1-C6) alkyl, - (C2-C6) alkenyl, - (C2-C6) alkynyl, - (C3-C8) cycloalkyl, - (C5-C8) cycloalkenyl, -phenyl, - (3 - at 5-bodies) heterocycle, -C (halo) 3, -CH (halo) 2, -CH2 (halo), -CN, -OH, -halo, -N3, -NO2, N (R7) 2, - CH = NR7, -NR7OH, -OR7, -COR7, -C (O) OR7, -OC (O) R7, -OC (O) OR7, -SR7, -S (O) R7, or -S (O) 2R7; each R7 is independently -H, - (C1-C6) alkyl, - (C2-C6) alkenyl, - (C2-C6) alkynyl, - (C3-C8) cycloalkyl, - (C5-C8) cycloalkenyl, -phenyl, - (3- to 5-bodies) heterocycle, -C (halo) 3, -CH (halo) 2, or CH2 (halo); each R8 is independently - (C1-C6) alkyl, - (C2-C6) alkenyl, - (C2-C6) alkynyl, - (C3-C8) cycloalkyl, - (C5-C8) cycloalkenyl, -phenyl, - (3 at 5 bodies) heterocycle, -C (halo) 3, -CH (halo) 2, -CH2 (halo), -CN, -OH, -halo, -N3, -NO2, -N (R7) 2, -CH = NR7, -NR7OH, -OR7, -COR7, -C (O) OR7, -OC (O) R7, -OC (O) OR7, -SR7, -S (O) R7, or -S (O) 2R7 ; each halo is independently -F, -Cl, -Br, or -I; m is an integer in a range from 0 to 2; n is an integer in a range from 0 to 3; p is an integer in a range from 0 to 2; q is an integer in a range from 0 to 6; r is an integer in a range from 0 to 5; and s is an integer in a range from 0 to 4. |
priorityDate | 2003-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 2084.