http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2321359-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d751513857e3e85f34dc83704dcfec5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92bd115d7fb2bb19f6f03dc97d8afa68 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa8659a6d3e7873e177cd619c98e9a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c341fe40c643f7ec8b1dd99196b098 |
publicationDate | 2010-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2321359-B1 |
titleOfInvention | P53 FUSION PROTEINS WITHOUT TRANSCRIPTION ACTIVITY AND ITS APPLICATIONS. |
abstract | P53 fusion proteins without activitynTranscription and its applications.n n n Fusion proteins are based on thenp53 protein, comprise an Mdm2 binding domain and / or a domainnof ubiquitilation, and lack all or part of the domainnresponsible for the DNA binding of said p53 protein, which hasnbeen replaced, totally or partially, by a tag peptide;ntherefore, said fusion proteins lack the activity ofntranscription of p53 proteins. Of application in the screening ofncompounds that inhibit the degradation of p53 protein via Mdm2nand / or via proteasome. |
priorityDate | 2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 267.