abstract |
Compounds of formula I in which R 1 is naphthyl, pyrrolidinyl, di-C 1-8 alkylamino, morpholinyl, C 1 -C 8 alkoxy, phenyl or thiophenyl, with phenyl and thiophenyl being optionally substituted with one to three substituents independently selected from C 1- alkyl C 8, C 1-C 8 alkoxy, trifluoromethyl, trifluoromethoxy, nitro and halogen; R 2 is hydrogen, C 1 -C 8 alkyl or halogen; R 3 is C1-C8 alkyl, halogen or trifluoromethyl; A 1 is C-R 3 or nitrogen; A 2 is piperidine or pyrrolidine, in which the nitrogen atom of the piperidine and pyrrolidone ring binds to A 3; A 3 is -S (O) 2- or -C (O) -; and n is zero, 1 or 2; and pharmaceutically acceptable salts thereof. |