abstract |
Compound of the formula ** see formula ** characterized in that: R 1, R 2, R 3 and R 4 are independently selected from hydrogen, halogen, hydroxy, alkyl, cycloalkyl, arylalkyl, aryl, alkoxy, alkoxyalkyl, haloalkyl, haloalkoxy , aryloxy, alkylcarbonyl, arylcarbonyl, alkylthio, arylthio, alkylsulfoxyl, arylsulfoxyl, alkylsulfonyl, arylsulfonyl, amino, nitro, cyano, alkoxycarbonyl, aryloxycarbonyl, mono- and di-alkylaminocarbonyl, alkylcarbonylamino, carboxy and heterocyclyl. with the proviso that at least one of the fractions R 1, R 2, R 3 and R 4 is not hydrogen; R 5 is hydrogen, alkyl or cycloalkyl; R 6 is alkyl or cycloalkyl; R 7 is hydrogen, halogen, alkyl, cycloalkyl, hydroxyalkyl, carboxyalkyl, carbamoylalkyl, alkoxycarbonylalkyl, aryloxycarbonylalkyl, formyl, alkylcarbonyl, alkoxy or alkylthio and salts thereof, solvates and pharmaceutically acceptable esters, for use as therapeutically active substance. |