http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2320430-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb878bd22f4da57c546e0088c43add26 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-22087 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2002-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8757c64198343e13d49d5eb3ed1a162e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7269810b69ee91b062824a43978a784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b19c582f5be33a8a4e4a8a87118a92c3 |
| publicationDate | 2009-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2320430-T3 |
| titleOfInvention | PORPHYRINS WITH EFFECTIVE SECTIONS OF MULTIPHOTONIC ABSORPTION IMPROVED FOR PHOTODYNAMIC THERAPY. |
| abstract | A compound of the following porphyrin structure: ** see formula ** in which: each R 1 is independently -TPA, -L-TPA, -H, -Ar, - (CH2) zCH3, -CH = CH2, - (CH2O) zG, -t-Butyl or -C (O) OG; each R2 is independently -TPA, -L-TPA, -H, -Ar, - (CH2) zCH3, -CH = CH2, - (CH2O) z-G, -t-Butyl or -C (O) OG; each R 3 is independently -TPA, -L-TPA, -H, -Ar, - (CH 2) zCH 3, -CH = CH 2, - (CH 2O) zG, -t-Butyl or -C (O) OG; or independently R 2 and R 3 are joined by -C4H4- to form a six-member ring; M is two hydrogen atoms or a metal ion; each z is independently an integer that varies from 1 to 20; each G is independently -H or a C1 to C20 alkyl; TPA is independently selected from the group consisting of the following structures TPA A to TPA H: ** see formula ** where in TPA A, R is independently selected from the group consisting of H, alkyl, alkyloxy and - (OCH2CH2) mOG, G is H or alkyl, and myn independently = 1 to 5; ** see formula ** where in TPA B, R is alkyl and n = 1 to 5; ** see formula ** where in TPA C, R is independently selected from the group consisting of H, CN, alkyl and alkyloxy, R '' is independently selected from the group consisting of alkyl, alkyloxyphenyl, phenyl and phenyl- (OCH2 CH2) mOG, G is H or alkyl, and m and n independently = 1 to 3; ** see formula ** where in TPA D, R '' is independently selected from the group consisting of alkyl, alkyloxyphenyl and phenyl- (OCH2 CH2) mOG, G is H or alkyl, and m and n independently = 1 to 5; ** see formula ** where in TPA E, R is independently selected from the group consisting of H, alkyl and - (OCH 2CH 2) mOG, R '' is alkyl, G is H or alkyl, and myn independently = 1 a 5; ** see formula ** where in TPA F, R is independently selected from the group consisting of H, alkyl and - (OCH 2CH 2) mOG, R '' is alkyl, G is H or alkyl, and myn independently = 1 a 3; ** see formula ** where in TPAG, R is independently selected from the group consisting of H, CN, alkyl, alkyloxy and - (OCH2CH2) mOG, R '' is independently selected from the group consisting of H, alkyl, alkyloxy and - (OCH2CH2) mOG, G is H or alkyl, and m = 1 to 6; and ** see formula ** where in TPA H, R is independently selected from the group consisting of alkyl, phenyl, alkyloxyphenyl and phenyl - [(OCH 2 CH2) mOG] x, G is H or alkyl, m = 1 a 4, and x = 1 to 4; where in TPA A to TPA H, the alkyl is from C 1 to C 20 and the selected TPA binds to the porphyrin structure at the point indicated by the wavy line; Ar is independently C 6H 4X, C 6H 3X 2, C 6H 2X 3, C 6HX 4 or C 6X 5, where X is independently F, Cl, Br, or I; and L is a binding residue between the porphyrin structure and the TPA and is independently selected from the group consisting of ethenyl, ethynyl, - (CH2) n- where n is equal to 1 to 20, ortho-phenyl, meta- phenyl, para-phenyl, -C (= O) - O- and 4-phenyl-2 '' - ethynyl; where at least one of R 1, R 2 or R 3 is a -TPA or -L-TPA moiety, and at least one of R 1, R 2 or R 3 is not -H or a -TPA or -L- moiety TPA |
| priorityDate | 2001-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 95.