| abstract |
A derivative (5R, 6S) -6-substituted amino-1,3-dioxepan-5-ol of formula [VII] ** see formula ** in which R 1 and R 2 are the same or different and each is a hydrogen atom, an alkyl or an aryl, or R 1 and R 2 combined form a cycloalkyl ring together with the adjacent carbon atom and R 4 is an amino protecting group selected from the group consisting of: an aralkylidene optionally substituted, an optionally substituted aralkyl, an optionally substituted acyl, an optionally substituted alkoxycarbonyl, an optionally substituted alkenyloxycarbonyl, an phenyloxycarbonyl, an optionally substituted aralkyloxycarbonyl, an optionally substituted lower alkylsilyl, an optionally substituted alkylthiocarbonyl, an optionally substituted alkylthiocarbonyl, an optionally substituted alkylthiocarbonyl substituted and an optionally substituted phosphinyl, an enantiomer thereof or a salt thereof. |