http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2318483-T4
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B62D7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B62D5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B66F9-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B60K7-00 |
filingDate | 2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba7f956e3e5d8b4d5eceb56566b2116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3268a6998be33ca851c36587ce990107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2269f0ad050e99a7d1a2662e8d660540 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3921caa109f58ecb176386fa925d56cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0293b1a12192b4be2e9d8049bc33f43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d42b8b77d50bcf12b60a5e79a04212e |
publicationDate | 2010-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2318483-T4 |
titleOfInvention | DERIVED FROM CONDENSED QUINOLINE AND ITS USE. |
abstract | A compound represented by formula (i) ** see formula ** in which R1 <br /> <br /> (1) is unsubstituted, <br /> <br /> (2) is a hydrogen atom <br /> <br /> (3) is a hydrocarbon group which optionally has substituents selected from the group of substituents A or <br /> <br /> (4) is acyl; R2 is <br /> <br /> (1) a hydrogen atom, <br /> <br /> (2) a hydrocarbon group that optionally has substituents selected from the group of substituents A, <br /> <br /> (3) hydroxy that optionally has a hydrocarbon group that optionally has substituents selected from the group of substituents A, <br /> <br /> (4) amino that optionally has 1 or 2 hydrocarbon groups that optionally have substituents selected from the group of substituents A, <br /> <br /> (5) a group represented by the formula -SR 20 in which R 20 is a hydrocarbon group optionally having substituents selected from the group of substituents A, <br / > <br /> (6) a group represented by the formula -S (O) R 21 in which R 21 is a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> (7) a group represented by the formula -S (O) 2R 22 in which R 22 is a hydrocarbon group having opc The substituents selected are the group of substituents A, <br /> <br /> (8) a heterocyclic group which optionally has substituents selected from the group of substituents A or <br /> <br /> (9) acyl; R3 <br /> <br /> (1) is unsubstituted, <br /> <br /> (2) is a hydrogen atom, <br /> <br /> (3) is a hydrocarbon group that has optionally substituents selected from the group of substituents A, <br /> <br /> (4) is hydroxy which optionally has a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> ( 5) it is amino that optionally has 1 or 2 hydrocarbon groups that optionally have substituents selected from the group of substituents A, <br /> <br /> (6) is a group represented by the formula -SR 20 in which R 20 is a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> (7) is a group represented by the formula -S (O) R 21 in which R 21 is a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> (8) is a group represented by the formula -S (O) 2R 22 wherein R 22 is a hydrocarbon group having optionally selected substituents the group of substituents A or <br /> <br /> (9) is acyl; R 4 and R 5 are the same or different and each is <br /> <br /> (1) a hydrogen atom, <br /> <br /> (2) a hydrocarbon group that optionally has substituents selected from the group of substituents A, <br /> <br /> (3) hydroxy that optionally has a hydrocarbon group that optionally has substituents selected from the group of substituents A, <br /> <br /> (4) amino that optionally has 1 or 2 hydrocarbon groups that optionally have substituents selected from the group of substituents A, <br /> <br /> (5) a group represented by the formula -SR 20 in which R 20 is a hydrocarbon group that optionally has substituents selected among the group of substituents A, <br /> <br /> (6) a group represented by the formula -S (O) R 21 in which R 21 is a hydrocarbon group having optionally substituents selected from the group of substituents A, <br /> <br /> (7) a group represented by the formula -S (O) 2R 22 in which R 22 is a hydrocarbon group having optionally selected substituents the group of substituents A or <br /> <br /> (8) acyl; R6 is <br /> <br /> (1) (cyclic group which optionally has substituents selected from the group of substituents A) carbonyl, <br /> <br /> (2) alkenylcarbonyl which optionally has substituents selected from the group of substituents A, <br /> <br /> (3) alkylcarbonyl having substituents selected from <br /> <br /> (i) cycloalkyl having optionally substituents selected from the group of substituents A, <br /> < br /> (ii) amino that optionally has 1 or 2 hydrocarbon groups that optionally have substituents selected from the group of substituents A and <br /> <br /> (iii) a heterocyclic group that optionally has substituents selected from the group of substituents A or <br /> <br /> (4) a heterocyclic group having optionally substituents selected from the group of substituents A; R 7, R 8, R 9 and R 10 are the same or different and each is <br /> <br /> (1) a hydrogen atom, <br /> <br /> (2) halogen, <br /> <br /> (3) cyano, <br /> <br /> (4) nitro, <br /> <br /> (5) a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> (6) hydroxy that optionally has a hydrocarbon group that optionally has substituents selected from the group of substituents A, <br /> <br /> (7) amino that optionally has 1 or 2 hydrocarbon groups which optionally have substituents selected from the group of substituents A, <br /> <br /> (8) a group represented by the formula -SR 20 in which R 20 is a hydrocarbon group which optionally has substituents selected from the group of substituents A, <br /> <br /> (9) a group represented by the formula -S (O) R 21 in which R 21 is a hydrocarbon group having optionally substituents selected from the substituent group entities A, <br /> <br /> (10) a group represented by the formula -S (O) 2R 22 in which R 22 is a hydrocarbon group having optionally substituents selected from the group of substituents A, <br /> <br /> (11) a heterocyclic group which optionally has substituents selected from the group of substituents A or <br /> <br /> (12) acyl; n is an integer from 1 to 5; --- represents that it is unsubstituted or a single link; == represents a single link or a double link; Y; The group of substituents A consists of <br /> <br /> (1) C1-6 alkyl which optionally has 1 to 3 substituents selected from (1 '') halogen, (2 '' hydroxy, (3 '') amino, (4 '') C6-10 -carbonylamino having optionally halogen-C1-6 alkyl, (5 '') C7-12 -oxycarbonylamino, (6 '') C1''6-carbonyloxy alkyl, <br /> <br /> (2) C2-6 alkenyl, <br /> <br /> (3) C 2-6 alkynyl, <br /> <br /> (4) C6-10 aryl, <br / > <br /> (5) C 7-19 aralkyl which optionally has 1 to 3 C 1-6 alkoxy groups, <br /> <br /> (6) hydroxy, <br /> <br /> (7 ) C1-6 alkoxy, <br /> <br /> (8) C6-10 aryloxy, <br /> <br /> (9) C7-12 aralkyloxy, <br /> <br /> (10) alkyl C 1-6-carbonyloxy, <br /> <br /> (11) alkenyl C2-6-carbonyloxy, <br /> <br /> (12) alkynyl C 2-6-carbonyloxy, <br /> <br /> (13) alkyl C1-6, <br /> <br /> (14) ariltio C6-10, <br /> <br /> (15) aralquiltio C 7-12, <br /> <br / > (16) carboxy, <br /> <br /> (17) C1-6-carbonyl alkyl, <br /> <br /> (18) C2-6-carbonyl alkenyl, <br /> <br /> (19) alkynyl C 2-6-carbonyl, <br /> <br /> (20) aryl C 6-10-carbonyl, <br /> <br /> (21) aralkyl C7-12-carbonyl, <br /> <br / > (22) C 1-6 alkoxycarbonyl, <br /> <br /> (23) C2-6 alkenyloxycarbonyl, <br /> <br /> (24) C2-6 alkynyloxycarbonyl, <br /> <br /> (25) C 6-10-carbonyl aryloxy, <br /> <br /> (26) C7-12-carbonyl aralkyloxy, <br /> <br /> (27) carbamoyl, <br /> <br /> (28) C1-6-carbamoyl mono-alkyl, <br /> <br /> (29) C 1-6-carbamoyl di-alkyl, <br /> <br /> (30) aryl C6-10-carbamoyl, <br /> <br /> (31) aralkyl C7-12-carbamoyl, <br /> <br /> (32) C 1-6 alkylsulfonyl, <br /> <br /> (33) C2-6 alkenylsulfonyl, <br /> <br /> (34) C 2-6 alkylsulfonyl, <br /> <br /> (35) amino, <br /> <br /> (36) mono -C1-6 alkylamino, <br /> <br /> (37) C1-6 di-alkylamino, <br /> <br /> (38) C2-6 mono-alkenylamino, <br /> <br /> (39) C 2-6 di-alkenylamino, <br /> <br /> (40) C2-6 mono-alkylamino, <br /> <br /> (41) C 2-6 di-alkylamino, <br /> <br /> (42) C6-10 arylamino, <br /> <br /> (43) C7-12 aralkylamino, <br /> <br /> (44) C 1-6 alkylcarbonylamino optionally having 1 to 3 substituents selected from (1 '') halogen, (2 '') C 1''6-carbonyl alkoxy, (3 '') mono- or di-C 1-6 alkylamino optionally substituted with hydroxy, (4 '') hydroxy, (5 '') C 1-6 alkylcarbonylamino, (6 '') carbamoylamino, (7 '') a heterocyclic group, ( 8 '') C6-10 arylamino, (9 '') (heterocyclic group) -carbonylamino and (10 '') C1-6 alkoxy, <br /> <br /> (45) C 3-8 cycloalkyl alkylcarbonylamino, <br /> <br /> (46) C2-6 alkenylcarbonylamino optionally having 1 to 3 substituents selected from (1 '') C6-10 aryl having optionally 1 to 3 substituents selected from halogen, C1 alkyl -6, C1-6 alkoxy and halogen-C 1-6 alkyl and (2 '') a heterocyclic group optionally having C 1-6 alkyl, <br /> <br /> (47) C2-6 alkynylcarbonylamino , <br /> <br /> (48) aryl C 6-10-carbonylamino having optionally 1 to 3 substituents selected from (1 '') halogen, (2 '') C1-6 alkyl having opium Only 1 to 3 substituents selected from halogen, hydroxy, amino and C1-6 alkylcarbonylamino, (3 '') C1-6 alkoxy optionally having 1 to 3 halogens, (4 '') C1-6 alkoxycarbonyl , (5 '') cyano, (6 '') carboxy, (7 '') mono- or di- C 1-6 alkylamino optionally having 1 to 3 substituents selected from hydroxy and C 1-6 alkoxy, (8 ' ') carbamoyl, (9' ') C 1-6 alkylcarbonylamino, (10' ') aminosulfonyl, (11' ') C 1-6 alkyl sulfonyl and (12' ') a heterocyclic group optionally having 1 to 3 substituents selected from C1-6 alkyl and oxo (= O), <br /> <br /> (49) C 7-12-carbonyl amino, <br /> <br /> (50) (heterocyclic group) -carbonylamino which may have 1 to 3 substituents selected from (1 '') amino, (2 '') C1-6 alkyl, (3 '') halogen-C1-6 alkyl, (4 '') C6-10 aryl, (5 '') oxo (= O) and (6 '') a heterocyclic group t |
priorityDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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