abstract |
A composition comprising: (a) metaxalone particles, or a salt thereof, wherein the metaxalone particles have an effective average particle size less than 2000 nm; and (b) at least one surface stabilizer, wherein the surface stabilizer is adsorbed on the surface of the metaxalone particles, with the proviso that the composition does not consist of 200 mg d-alpha-tocopherol succinate; Cremophor RH 40 200 mg; glycerol dibehenate (Compritol 888) 100 mg; glycerol distearate (Precirol) 80 mg; and metaxalone 300 mg. |