| abstract |
Use of a compound for the manufacture of a medicament for the treatment of an autoimmune disease, wherein the compound is a compound of formula ** see formula ** an N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein Q is 3-pyridyl, 4-pyridyl, naphthalenyl, C 3-6 cycloalkyl, phenyl, 1,3-benzodioxolyl, 2,3-dihydro-benzofuranyl, 2,3-dihydro- 1,4-benzodioxynyl, benzthiazolyl, indazolyl, benzimidazolyl or imidazopyridyl, wherein said phenyl, 3-pyridyl, 4-pyridyl, benzthiazolyl or imidazopyridyl may be optionally substituted with up to three substituents selected from halo, cyano, C1-6 alkyl, C1-alkyl -6-oxy or polyhalo-C1-6 alkyl; L is 3-halophenyl; or L is imidazolyl, imidazothiazolyl, pyrimidinyl, thienyl, thiazolyl, furanyl, 3-pyridyl, 4-pyridyl, pyrazolyl, indolyl, indazolyl, quinolinyl, benzofuranyl, pyrrolopyridyl, imidazopyridyl, imidazopirazinilo, imidazopyrimidinyl, imidazopyridazinyl, pyrazolopyridyl, each heterocycle being optionally substituted with one, two, three or four substituents each independently selected from halo, amino, C 1-6 alkyl, polyhalo-C 1-6 alkyl, aminocarbonyl or C1-6-C alkyl (= O) -NH-. |