| abstract |
A compound having the formula ** see formula ** where -X-Ar1 is -O-pyridyl, Y is -N (R12) -S (O) m- where R 12 is hydrogen or C 1 -C 10 alkyl; and the subscript m is an integer from 0 to 2; R 1 is C1-C10 alkyl, C1-C10 haloalkyl, -C (O) R 14, -CO2R 14 or -C (O) NR 15 R 16, R 14 is hydrogen or C 1 -C 10 alkyl; R 15 and R 16 are each independently hydrogen or C1-C10 alkyl; R 2 is phenyl optionally substituted with one to three substituents independently selected from halogen, -OCF3, -OH, -O-C1-C8 alkyl, -C (O) -C1-C8 alkyl, -CN, -CF3, -C1 alkyl -C8 and NH2 with the proviso that when Ar 1 -X- is 5-chloro-3-pyridyloxy, R 1 is carboethoxy and Y is -NHSO 2- and the groups Ar 1 -X-, R 1 and -YR 2 occupy positions at carbons 2, 1 and 5 of the benzene ring, respectively, R 2 is different from 4-tolyl or 2,4-dichloro-5-methylphenyl. |