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filingDate 2003-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2316763-T3
titleOfInvention COMPOUNDS AS SEMAPHORINE INHIBITORS.
abstract Compound represented by the general formula (1): (see formula) in which R1, R2, R3 and R4 represent one of the following [I] to [IX]: [I] R1 represents a hydrogen atom or a carboxyl group , R2 represents a hydrogen atom or a hydroxyl group, and R3 and R4, join to form a divalent group of formula (2) :( see formula) in which R5 represents a hydrogen atom or a carboxyl group and R6 represents a hydrogen atom or a hydroxyl group; [II] R1 represents a hydrogen atom or a carboxyl, R2 represents a hydrogen atom or a hydroxyl group, and R3 and R4, join to form a divalent group of formula (3): (see formula) in which R5 and R6 have the same meanings as before; [III] R1 represents a hydrogen atom or a carboxyl group, R2 represents a hydrogen atom or a hydroxyl group, and R3 and R4, join to form a divalent group of formula (4) :( see formula) in which R5 and R6 have the same meanings as before; [IV] R 1 represents a hydrogen atom or a carboxyl group, R 2 represents a hydrogen atom or a hydroxyl group, and R 3 and R 4, join to form a divalent group of formula (5): (see formula ) in which R 5 and R 6 have the same meanings as before; [V] R 1 represents a hydrogen atom or a carboxyl group, R 2 represents a hydrogen atom or a hydroxyl group, R 3 represents a hydrogen atom and R 4 represents a group of formula (6): (see formula) [VI] R 1 represents a hydrogen atom or a carboxyl group, R 2 represents a hydrogen atom or a hydroxyl group and R 3 and R 4 join to form a divalent group of formula (7): (see formula) in which R 5 and R 6 have the same meanings as before; [VII] R 1 represents a hydrogen atom or a carboxyl group, R 2 represents a hydrogen atom or a hydroxyl group and R 3 represents a group of formula (8): (see formula) in which R 7 represents an atom of hydrogen or a carboxyl group and R 8 represents a hydrogen atom or a hydroxyl group and R 4 represents a group of formula (9); (see formula) in which R 5 represents a carboxyl group, and R 6 has the same meaning as before; [VIII] R 1 represents a carboxyl group, R 2 represents a hydroxyl group, and R 3 and R 4 join to form a divalent group of formula (10): (see formula) in which R 5 represents a carboxyl group and R 6 represents a hydroxyl group; [IX] R 1 represents a carboxyl group; R 2 represents a hydroxyl group, and R 3 and R 4 join to form a divalent group of formula (11): (see formula) or a pharmaceutically acceptable salt thereof.
priorityDate 2002-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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