http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2313667-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6042509de7544921c96de43b9da1438 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
filingDate | 2006-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbeda6dc3464c108affdff096cbefe2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e649621b8d1fd9bf442006bd8da57084 |
publicationDate | 2009-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2313667-T3 |
titleOfInvention | DERIVATIVES OF 2-METHYL-4-PHENYL-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE AS FOR THE TREATMENT OF INFERTILITY. |
abstract | A 2-methyl-4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivative according to Formula 1. (See formula) in which R 1 is (C 1-6) alkyl , (C2-6) alkenyl or (C2-6) alkynyl; R 2 is halogen; R 3 is SO2NR 5 R 6 or (C1-4) alkoxy, optionally substituted with one or more fluorine atoms; X is O or NR 7; R 4 is R 8 -alkyl (C2-8), R 8 -alkenyl (C3-8), R 8 -alkynyl (C3-8) or R 8 -alkoxy (C2-4) -alkyl (C2-4); Z is CN or NO 2; R 5 and R 6 are independently H or (C 1-4) alkyl; or R 5 together with R 6 and the N to which they are attached form a 3-8-saturated saturated ring that optionally contains another heteroatom selected from O and S; R 8 is OH, (C 1-4) alkoxy, NH 2; NR 9 C (O) R 11, NR 9 SO2R 11 or C (O) NR 9 R 10; R 7 and R 9 are independently H or (C 1-4) alkyl; R 10 is (C1-4) alkyl, (C1-4) alkoxy (C1-4) alkyl, or phenyl (C1-4) alkyl or heteroaryl (C2-5) (C1-4) alkyl, both optionally substituted in the (hetero) aromatic ring with one or more substituents selected from OH, NH2, halogen, NO2, CF3, CN, (C1-4) alkyl, (C1-4) alkoxy and (di) (C1-4) alkyl amino; R 11 is (C1-4) alkyl, (C2-4) alkenyl, (C2-4) alkynyl, (C1-4) alkoxy (C1-4) alkyl, (C3-6) cycloalkyl, (C1-4) alkoxy , (di) alkyl (C1-4) amino, or phenyl or heteroaryl (C2-5), both optionally substituted on the (hetero) aromatic ring with one or more substituents selected from OH, NH2, halogen, NO2, CF3, CN , (C1-4) alkyl, (C1-4) alkoxy and (di) (C1-4) alkyl amino; or a pharmaceutically acceptable salt thereof. |
priorityDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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