http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2311985-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b58f981963f6d55d627139e778c4ef7b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c6f57e81bb19aa03580d7663e822c95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b67808683a1b8fd67fc476ea4f561a5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f17af2f195d5697116e8aa9a26cb857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa5e557e74795233608e68b2d36d7af7 |
| publicationDate | 2009-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2311985-T3 |
| titleOfInvention | DERIVATIVES (POLI) EPIPODOFILOTOXINA AMINOACETAMIDE, ITS PREPARATION PROCEDURE AND ITS APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENTS. |
| abstract | Compounds of general formula (I): (See formula) in which: * R 1 and R 2 represent, independently of each other, a hydrogen atom or a methyl radical, - R3 and A together form a C3-C8 or * ring R3 represents a radical selected from the group consisting of a hydrogen atom, a C1-C4 alkyl radical and a benzyl radical, and A represents a radical selected from the group consisting of a hydrogen atom, a C1-C4 alkyl radical , a benzyl radical and a group of formula (II): (See formula) in which: a is between 2 and 5 R4 and B together form a C3-C8 or R4 ring represents a radical selected from the group constituted by a hydrogen atom, a C1-C4 alkyl radical and a benzyl radical, it is possible that R 3 and R 4 are connected by an alkylene chain comprising 2 or 3 carbon atoms, and B represents a radical selected from the group consisting of: - a hydrogen atom, - a radica C1-C4 alkyl, - a benzyl radical, - a group of formula (III): (See formula) in which b and c can be comprised, independently of one another, between 2 and 5, and R 5 to R 7 independently represent each other, a radical selected from the group consisting of a hydrogen atom, a C1-C4 alkyl radical and a benzyl radical, it being possible that R 4 and R 5 and / or R 5 and R 6 and / or R 6 and R 7 is connected by an alkylene chain comprising 2 or 3 carbon atoms, - and a group of formula (IV): (See formula) in which c can be comprised between 2 and 5, and R 8 and R 9 represent , each independently of each other, a hydrogen atom or a C1-C5 alkyl radical, it being possible that R 4 and R 8 are connected by an alkylene chain comprising 2 or 3 carbon atoms, or R 8 and R 9 together a C3-C8 ring, or its pharmaceutically acceptable salts, in particular its addition salts, with inorganic or organic acids. |
| priorityDate | 2004-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.