| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fb41c43482788ffed24bc9363d81ee8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00c9314159fffd8d749d23c813691f5c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 |
| filingDate |
2006-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ccc5e27afa3480db47eb419a32c26f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fedb55390a989da55dc4d0f49e2cf70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e71d5a08b75dab5dac9f0efed4e27c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8e96f929bc0e9a744ead4d96b54efb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07a3ea50fc1a2e8695eeb2bb73300a2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5dfe6d0e4761405039ff2dae172a4d4 |
| publicationDate |
2009-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2311426-A1 |
| titleOfInvention |
A PROCEDURE FOR THE PREPARATION OF RUPATADINA AND ITS SALTS. |
| abstract |
A procedure for the preparation ofnRupatadine and its salts.n n n Rupatadine is synthesized by thenN-alkylation catalyzed by phase transfernof desloratadine in a biphasic solvent system using anaqueous base by the reaction of a compound ofnformula-A:n n n n onen n n n with desloratadine at a temperature of up ton50 ° C, in which the selected solvent is an organic solventnimmiscible in water. Rupatadine also converts to fumarate fromnrupatadine by the reaction of rupatadine in a ketone solventnwith an alcoholic solution of fumaric acid. |
| priorityDate |
2005-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |