| abstract |
A compound of the following formula Ia or a salt thereof: (See formula) in which the symbols have the following meanings and, each time they are presented, are independently selected: G is an aryl or heterocycle group, said mono group being or polycyclic, and which is optionally substituted in one or more positions; Z is O; n = 1 or 2; A1 is CR 7; A2 is CR 7; Y is O, S, S = O, SO2, NR 7, C = O, OC = O, NR 1 C = O, C = CR 8 R 8 '', (CR 7 R 7 '') n, in the that n = 1-3; W is CR 7 R 7 '' -CR 7 R 7 '', CR 8 = CR 8 '', CR 7 R 7 '' -C = O, NR 9 -CR 7 R 7 '', N = CR 8, N = N, NR 9 -NR 9 '', S-CR 7 R 7 '', SO-CR 7 R 7 '', SO2-CR 7 R 7 '', substituted cycloalkyl or cycloalkyl, substituted cycloalkenyl or cycloalkenyl, heterocycle or substituted heterocycle, or substituted aryl or aryl; Q1 is H, substituted alkyl or alkyl, substituted alkenyl or alkenyl, substituted cycloalkyl or substituted cycloalkyl, substituted cycloalkenyl or cycloalkenyl, substituted heterocycloalkyl or heterocycloalkyl, substituted arylalkyl or arylalkyl, substituted alkynyl or alkynyl, substituted hetero or aryl heterocycle , CN, R 1 OC = O, R 4 C = O, R 5 R 6 NC = O, HOCR 7 R 7 '', nitro, R 1 OCH2, R 1 O, NH2, C = OSR 1, SO2R 1 or NR 4 R 5; Q2 is H, substituted alkyl or alkyl, substituted alkenyl or alkenyl, substituted cycloalkyl or substituted cycloalkyl, substituted cycloalkenyl or cycloalkenyl, substituted heterocycloalkyl or heterocycloalkyl, substituted arylalkyl or arylalkyl, substituted alkynyl or alkynyl, heteroaryl or substituted heterocycle , halo, CN, R 1 OC = O, R 4 C = O, R 5 R 6 NC = O, HOCR 7 R 7 '', nitro, R 1 OCH2, R 1 O, NH2, C = OSR 1, SO2R 1 or NR 4 R 5; L is a link; R 1 and R 10 are each independently H, substituted alkyl or alkyl, substituted alkenyl or alkenyl, substituted alkynyl or alkynyl, substituted cycloalkyl or cycloalkyl, substituted cycloalkenyl or cycloalkenyl, substituted heterocycle or heterocycle, substituted cycloalkylalkyl or cycloalkylalkyl, cycloalkenyl or cycloalkenyl , heterocycloalkyl or substituted heterocycloalkyl, substituted aryl or aryl, substituted arylalkyl or arylalkyl; R 2 is substituted alkyl or alkyl, substituted alkenyl or alkenyl, substituted alkynyl or alkynyl, substituted cycloalkyl or cycloalkyl, substituted cycloalkenyl or cycloalkenyl, substituted heterocycle or heterocycle, cycloalkylalkyl or substituted cycloalkylalkyl, cycloalkenylalkyl or substituted cycloalkyl, cycloalkyl, substituted alkyl substituted aryl, arylalkyl or substituted arylalkyl; R 4 is ... |