http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2310492-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d12b35c0dd9adfb167b3b4f383afe93 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-042 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 |
| filingDate | 2007-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90ca06a171e6e56e12714fbd9c7a60d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_093b644966c4f3c939c1fa71941bfc85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f866409cfc9a92e189d512eeab419ea2 |
| publicationDate | 2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2310492-B1 |
| titleOfInvention | PROCEDURE FOR THE DEVELOPMENT / DISPROTECTION OF SYNTHESIZED COMPOUNDS BY SOLID PHASE. |
| abstract | Procedure for de-anchoring / unprotectionnof compounds synthesized by solid phase.n n n Organic compounds are prepared by the methodnof the solid phase by undocking / unprotecting ancompound directly attached without bifunctional spacersn("linkers") to functionalized resins comprisingnpolystyrene, by treating said resin bound compoundnwith an acidolytic reactive mixture comprising acidntrifluoroacetic and at least one silane of formulanH_ {n} SiR_ {m} X_ {y} (I), where R is a radical that is selectednof the group consisting ofn(C 1 -C 4) -alkyl and phenyl;nX is independently selected from Cl, Br, I andntrifluoromethanesulfonate; n, m, e and are integers that arenindependently select between 0 and 4 with the proviso that nn+ m + y = 4; in the absence of Lewis bases. This procedure isnespecially useful for the de-anchoring / deprotection of peptides fromnfunctionalized resin, in particular amide peptides or peptidesnacid prepared by the Fmoc / t Bu strategy. |
| priorityDate | 2007-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.