http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2309534-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6d76960d9b399aef783022e33a65ac1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2004-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d478b457b665840bb4febabf6468eaa7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7d4ef654bbcd4fdc3dada8c0e3c8b31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67406b71162d8b9dfe2c880f2f2e447a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2931aced3d36776b3029b949df5ea88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11b03dde7c33f9d68c2802ffa8631c46 |
| publicationDate | 2008-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2309534-T3 |
| titleOfInvention | DERIVATIVES OF PIRROLOIMIDAZOL, ITS PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, AND ITS USE AS NOOTROPIC AGENTS. |
| abstract | Compound of general formula (I) (See formula) in which: A is selected from carbocyclic aromatic groups, heterocyclic aromatic groups and C1-4 arylalkyl; R1 is selected from: - hydrogen, - C1-7 arylalkyl, optionally substituted on the aryl moiety with one or more groups selected from hydroxy, C1-4 alkoxy, halogen, C1-4 haloalkyl; - C1-7 heterocyclylalkyl, optionally substituted on the heterocyclyl moiety with one or more groups selected from C1-4 alkyl and hydroxy; - C1-7 alkyl, optionally interrupted by an oxygen or sulfur atom or optionally substituted at any position by one or more groups selected from hydroxy, thio, amino, carboxyl, aminocarbonyl, guanidinyl. R2 is selected from hydrogen, C1-4 alkyl, C1-4 arylalkyl and phenyl; or R1 and R2, taken together, form a saturated carbocyclic ring containing between 3 and 8 carbon atoms; R3 is selected from hydrogen, C1-4 alkyl, C1-4 arylalkyl, CONH2 and COOR5 in which R5 is selected from hydrogen and C1-4 alkyl; R4 is selected from hydrogen, C1-4 alkyl, aryl, C1-4 arylalkyl and heterocyclyl; and n is 2, 3 or 4; in the form of a racemic mixture or in the form of enantiomers, and their pharmaceutically acceptable salts or solvates, in which: the term "carbocyclic aromatic group" means aromatic rings alone or fused with 6 to 12 ring members, optionally substituted. The terms "heterocyclic aromatic group" and "heterocyclyl" mean single or fused aromatic rings, each ring having 5 to 12 members and comprising up to four heteroatoms, selected from oxygen, sulfur and nitrogen, optionally substituted; the term "aryl" means unsaturated rings alone or fused, each ring with between 5 and 8 members, and preferably 5 or 6 members, optionally substituted; Unless otherwise specified, "optionally substituted" groups are groups optionally substituted with 1 to 3 substituents, preferably selected from Me, Et, i-Pr, OH, COOEt, COOH, CH2OH, SO2NH2, SO2Me, OMe, Cl, F, CN and CF3, and more preferably between Me, Et, i-Pr, OH, CN, Cl and CF3; the substituents may be in any position of the group to be substituted. |
| priorityDate | 2003-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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