http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2308504-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19229fe7f5fcc0a484adc464fc5bdb8d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 2005-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf2ec577e0716918967fe4a3d37d80d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d80313fd46d8c91b7e7a5c3af8f4416d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13cfa980e80618b01d1f1b0f530627b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ddf53d0a784a747cb95cf5d10e89cb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bfd97a3be4577c6c25781ed42b0ce9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf9037986e3ada4c379f6ed7757aafad |
| publicationDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2308504-T3 |
| titleOfInvention | TETRAHYDROPIRIDOTIOFENOS FOR USE IN THE TREATMENT OF CANCER. |
| abstract | Compounds of formula I: (See formula) in which: Ra is -C (O) R 1, -C (O) OR 2, -C (O) SR 2, -C (O) N (R 3) R 4, -S (O) 2R 1 or -S (O) 2N (R 3) R 4 and Rb is optionally substituted with Rca and / or Rcb, and is Har, or Rb is Cyc, or Rb is chromenyl; in which R 1, R 2, R 3 may be the same or different and are independently selected from the group consisting of: hydrogen, C 1-7 alkyl, C 3-7 cycloalkyl, Ar, Har and Het, in which each of said C1-7 alkyl, C3-7 cycloalkyl, Ar, Har and Het may be unsubstituted or optionally substituted with at least one substituent independently selected from R 5; each R 4 is independently selected from the group consisting of: hydrogen, C 1-7 alkyl or C 3-7 cycloalkyl, wherein each of said C 1-7 alkyl and C 3-7 cycloalkyl may be unsubstituted or optionally substituted with at least one substituent independently selected from R 5; R 5, Rca and Rcb may be the same or different and are independently selected from the group consisting of: C1-7 alkyl, C3-7 cycloalkyl, Ar, Har, Het, halogen, trifluoromethyl, nitro, cyano, guanidino, amidino, -C (O) R 6, -C (O) OR 7, -C (O) N (R 8) R 9, -S (O) 2R 6, -S (O) 2N (R 8) R 9, -N (R 10) C (O) R 6, -N (R 10) C (O) OR 7, -N (R 10) C (O) N (R 8) R 9, -N (R 10) S (O) 2R 6, -N (R 10) S (O) 2N (R 8) R 9, -OC (O) R 6, -OC (O) N (R 8) R 9, -OR 7, -N (R 8) R 9 or -SR 7, wherein each of said C1-7 alkyl, C3-7 cycloalkyl, Ar, Har and Het may be unsubstituted or optionally substituted with at least a substituent independently selected from R 11; R 6, R 7 and R 8 may be the same or different and are independently selected from the group consisting of: hydrogen, C 1-7 alkyl, C 3-7 cycloalkyl, Ar, Har and Het, in which each of said C1-7 alkyl, C3-7 cycloalkyl, Ar, Har and Het may be unsubstituted or optionally substituted with at least one substituent independently selected from R 12; each R 9 is independently selected from the group consisting of: hydrogen, C1-7 alkyl or C3-7 cycloalkyl, in which each of said C1-7 alkyl and C3-7 cycloalkyl may be unsubstituted or optionally substituted with at least one substituent independently selected from among R 12; each R 10 is independently selected from the group consisting of: hydrogen, C1-7 alkyl or C3-7 cycloalkyl; R 11 is selected from the group consisting of: R 5 as defined above; each R 12 is independently selected from the group consisting of: R 5 as defined above; each Ar is independently selected from phenyl and naphthyl; every Har is ... |
| priorityDate | 2004-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 509.