http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2308471-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-14 |
| filingDate | 2005-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d4665fcf202c44939e1a912fb850a23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f3c0086d706ce49224f58ba705704fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cde0c30811b7dc7bee7f7a84b75abf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24600a9024e6b28011fe03c5480b3d4b |
| publicationDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2308471-T3 |
| titleOfInvention | OPIOID RECEIVERS ANTAGONISTS. |
| abstract | A compound of formula (I) (See formula) in which: j is 1 or 2; y is 0, 1 or 2; and z is 0, 1 or 2; p is 0, 1 or 2; E is O or NH; and wherein each of X1, X2, X3, X4, X5 or X6 is C, CH or N; with the proviso that each of the A or C rings has no more than 2 nitrogen atoms; and with the proviso that Ring B has 0 or 1 double bonds excluding the tautomeric links of rings A and C; R 1 and R 2 are independently selected from hydrogen, methyl, ethyl, propyl, isopropyl, 2-methylpentyl, t-butyl, cyclopropyl, phenyl, (See formula) and in which R 1 and R 2 can optionally combine between yes to form a nitrogen containing heterocycle with 4, 5, 6 or 7 members, in which the nitrogen containing heterocycle may also have substituents selected from the group consisting of oxo, amino, C1-C8 alkyl, C2-C8 alkenyl, alkynyl C2-C8, phenyl, C1-C8 alkylaryl, C1-C8C (O) alkyl, C1-C8CO (O) alkyl, halo, C1-C8 haloalkyl; R 3 and R 30 are each independently selected from hydrogen, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, phenyl, aryl, C1-C8 alkylcycloalkyl and C1-C8 alkylaryl; R a and R b are each independently selected from hydrogen and C1-C3 alkyl or combined with their respective carbon atoms to form the vinyl diradical -CH = CH-; R 4 and R 5 are each independently selected from hydrogen, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C1-C8 alkoxy, halo, C1-C8 haloalkyl, phenyl, aryl, C1-C8 alkylaryl , (CH2) mNSO2 C1-C8 alkyl, (CH2) mNSO2 phenyl, (CH2) mNSO2 aryl, -C (O) C1-C8 alkyl and C (O) O C1-C8 alkyl; wherein each R 4 and R 5 are attached to their respective rings only at the carbon atoms; in which m is 1 or 2; and n is 1, 2 or 3; R 6 and R 7 are each independently selected from hydrogen, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, -C (O) C1-C8 alkyl, SO2 C1-C8 alkyl, SO2 C1-alkylaryl C8, SO2 C1-C8 alkylheterocyclic, aryl, C1-C8 alkylaryl, C3-C7 cycloalkane, C1-C6 alkylcycloalkane, (CH2) nC (O) OR 8, (CH2) nC (O) R 8, (CH2) nC ( O) R 8, (CH2) mC (O) NR 8 R 8 and (CH2) mNSO2R 8; wherein each of the alkyl, alkenyl and aryl groups are optionally substituted with one to five groups independently selected from C1-C8 alkyl, C2-C8 alkenyl, phenyl and C1-C8 alkylaryl; and in which ... |
| priorityDate | 2004-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.