| abstract |
A multilayer regulated release tablet consisting of (a) an active layer consisting of: (i) 0.050-20% by weight of ropinirole, including its pharmaceutically acceptable salts, (ii) swollen hydrophilic polymeric substances and / or gel and / or erode by contact with aqueous liquids, (iii) lipophilic substances, and (iv) 5-50% by weight of adjuvant substances, in which the weight ratio of hydrophilic polymeric substances with respect to lipophilic substances contained in said active layer, it is in the range of 7: 1 to 1: 1; and (b) one or more barrier layers that limit the transfer surface of the active layer, whose barrier layers contain one or more of: hydrophilic polymeric substances that swell and / or gel and / or erode upon contact with aqueous liquids , lipophilic substances and adjuvant substances, the tablet of which is optionally coated. |