http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2307416-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f9db723f41b9245df17b048ca637ad2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e80d79d20a3cd9850ffbf2c03388e0b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_221102230855f9ae84703ec5f67a6024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9705cdd718df708359db4b157d036b0c |
publicationDate | 2009-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2307416-B1 |
titleOfInvention | PROCEDURE TO OBTAIN MONTELUKAST. |
abstract | Procedure to obtain Montelukast.n n n The present invention relates to a process for the synthesis of (1- {1- (R) - (E) - {3- [2- (7-chloroquinolin-2-yl) -vinyl] -phenyl} -3 acid - [2- (1-Hydroxy-1-methyl-ethyl) -phenyl] -propylsulfa- nylmethyl} -cyclopropyl) -acetic acid or its salts, which comprises the reaction between 7-chloro-2-vinyl quinoline and a compound of formula (I)n n n n 100n n n n in which X is a halogen atomnor a group of formula -OSO2R, in which R is selected fromnthe group consisting of CF 3, tolyl, methyl andnF;n n n in the presence of a catalyst based onnpalladium. The invention is also directed to intermediate compounds of thenprocess. |
priorityDate | 2007-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.