http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2307168-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d904e68b6e0b4f6ce1d0cbcd02d8a99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 |
| filingDate | 2005-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c8cce697dbee8d52255bb8b7c348edd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290421a83397f9f8bc5b17a4c81d7835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1556daf5dea94715d05e83b95b13f18 |
| publicationDate | 2008-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2307168-T3 |
| titleOfInvention | NEW QUATERNIZED QUINUCLIDINE ESTERS. |
| abstract | A compound of formula (I): (See formula) wherein B represents a hydrogen atom or a group selected from -R 1, -OR 1, hydroxy, -O (CO) R 1, cyano and an optionally non-aromatic heterocyclyl substituted containing one or more heteroatoms, wherein R 1 is selected from the group consisting of hydrogen atoms, optionally substituted C1-C8 alkyl, optionally substituted C2-C8 alkenyl and optionally substituted C3-C8 cycloalkyl n is an integer of 0 to 4; A represents a group selected from -CH2-, -CH = CR 3 -, -CR 3 = CH-, -CR 3 R 4 -, -O-, -CO-, -O- (CH2) 2-O- in where R 3 and R 4 each independently represents a hydrogen atom or a C 1-8 alkyl group; m is an integer from 0 to 8; p is an integer from 1 to 2 and the substitution in the azonia-bicyclic ring may be in position 2, 3 or 4 including all possible configurations of asymmetric centers; D is a group selected from: (See formula) wherein R 5 represents a group selected from phenyl, 2-thienyl, 3-thienyl, 2-furanyl, 3-furanyl, which group may be optionally substituted with one or more substituents Ra ; R 6 represents a group selected from 2-thienyl, 3-thienyl, 2-furanyl, 3-furanyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, benzyl and phenylethyl, said group being optionally substituted with one or more Rb substituents; R 7 represents a hydrogen atom or a group selected from hydroxyl, hydroxymethyl and methyl; Q represents a single bond or a group selected from -CH2-, -CH2CH2-, -O-, -O-CH2-, -S-, -S-CH2-, and -CH = CH-; Ra and Rb independently represent a group selected from halogen atoms, optionally substituted C1-8 alkyl, optionally substituted C1-C8 alkoxy, hydroxy, trifluoromethyl, nitro, cyano, -COOR 8, -NR 8 R 9 where R 8 and R 9 independently represent a hydrogen atom or a C1-8 alkyl group and is an integer from 0 to 3, X- represents a pharmaceutically acceptable anion of a monovalent or polyvalent acid; with the proviso that the group B- (CH2) nA- (CH2) m- is not a C1-4 linear alkyl group and with the additional condition that the compound is not one of: 1-Allyloxycarbonylmethyl-3- (2- hydroxy-2,2-di-thiophene-2-yl-acetoxy) -1-azoniabicyclo- [2.2.2] octane; and 1-carboxymethyl-3- (2-hydroxy-2,2-di-thiophene-2-yl-acetoxy) -1-azoniabicyclo- [2.2.2] octane. |
| priorityDate | 2004-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.