| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_806f0a3a49d26f0b2efb79a3ea184ce9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2000-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bcec85428e25b65908ab5a83f4ae4b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54a29b572f2dcbcc716a734f21d3680
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad0cc4d443c6a4d128590afa726c8d41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ccadaf4f7f1426c50f3f6c49bcae2f2 |
| publicationDate |
2008-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2304957-T3 |
| titleOfInvention |
MODIFIED CYTOQUINE FOR STABILIZATION. |
| abstract |
A cytokine stabilization method comprising the following steps: a) mutating the amino acid sequence of the cytokine so that hydrophobic residues exposed to the solvent are removed by amino acid substitution; and b) mutating the amino acid sequence of the cytokine so that helix stabilizing residues are introduced; such that during the folding of the cytokine, an intermediary formed during the folding of the cytokine is destabilized relative to the cytokine in its folded state. |
| priorityDate |
1999-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |