http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2303244-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f874eb11d4775decc4fd06a6071a4c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-538 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-538 |
| filingDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dee7c02b49521533bf5baea3f7db59a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2349818ede6df722fb5474ea760951d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc91426b0af437f5387a31e3cce3ac9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a43c44f19c407f38b6d33c895629a49d |
| publicationDate | 2008-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2303244-T3 |
| titleOfInvention | DERIVATIVES OF (1,10B-DIHIDRO-2- (AMINOCARBONIL-PHENYL) -5H-PIRAZOLO (1,5-C) (1,3) BENZOXAZIN-5-IL) PHENYL METANONE AS INHIBITORS OF HIV VIRAL REPLICATION. |
| abstract | A compound having the formula (See formula) its N-oxide, stereoisomeric form or its salt, where a is zero, 1, 2, 3, 4 or 5; R1 is hydrogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-12 cycloalkyl, Het, aryl or C1-10 alkyl substituted with a substituent selected from the group consisting of Het, aryl, C3-12 cycloalkyl, amino and mono- or disubstituted amino where the substituents of the amino group are each individually selected from C1-10 alkyl, C2-10 alkenyl, C3-12 cycloalkyl, Het and aryl; R2 is hydrogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-12 cycloalkyl, Het, aryl or C1-10 alkyl substituted with a substituent selected from the group consisting of Het, aryl, C3-12 cycloalkyl, amino and mono- or disubstituted amino where the substituents of the amino group are each individually selected from C1-10 alkyl, C2-10 alkenyl, C3-12 cycloalkyl, Het and aryl; or R1 and R2 taken together with the nitrogen atom to which they are attached form a saturated or partially saturated heterocycle of 5 to 12 members, whose heterocycle may be optionally substituted with C1-10 alkyl, C2-10 alkenyl, C2 alkynyl -10, C3-12 cycloalkyl, C1-6 alkyloxycarbonyl, Het, aryl or C1-10 alkyl substituted with a substituent selected from the group consisting of Het, aryl, C3-12 cycloalkyl, amino and mono- or disubstituted amino where the substituents of the amino group are each individually selected from C1-10 alkyl, C2-10 alkenyl, C3-12 cycloalkyl, Het and aryl; R3 is carboxyl, halogen, nitro, C1-10 alkyl, C3-12 cycloalkyl, polyhalo-C1-10 alkyl, cyano, amino, mono- or disubstituted amino, aminocarbonyl, mono- or disubstituted aminocarbonyl, C1- alkyloxy 10, C1-10 alkylthio, C1-10 alkylsulfonyl, pyrrolidinyl, piperidinyl, homopiperidinyl, morpholinyl, thiomorpholinyl or piperazinyl optionally substituted with C1-10 alkyl, where the substituents on any of the amino groups are each individually selected C1-10 alkyl, C2-10 alkenyl, C3-12 cycloalkyl, Het and aryl; aryl is phenyl optionally substituted with one or more substituents selected from the group consisting of C1-10 alkyl, polyhalo-C1-10 alkyl, C1-10 alkyloxy, C1-10 alkylthio, C1-10 alkylsulfonyl, nitro, cyano , halo, C3-7 cycloalkyl, C1-10 alkylcarbonyl, carboxyl, C1-10 alkyloxycarbonyl, amino, mono- or disubstituted amino, aminocarbonyl, mono- or disubstituted aminocarbonyl, where the substituents of any of the amino groups are selected each individually of phenyl, C1-10 alkyl, C2-10 alkenyl, C3-7 cycloalkyl, pyrrolidinyl, piperidinyl, homopiperidinyl or piperazinyl optionally substituted with C1-10 alkyl; Het is a monocyclic or bicyclic aromatic heterocycle, saturated or partially saturated, of 5 or 6 members with one or more heteroatoms each individually selected from nitrogen, oxygen, or sulfur, and whose heterocycle may be optionally substituted with one, or when possible , with more than one substituent selected from the group consisting of C1-10 alkyl, polyhalo-C1-10 alkyl, C1-10 alkyloxy, C1-10 alkylthio, C1-10 alkylsulfonyl, nitro, cyano, halo, C3-7 cycloalkyl, C1-10 alkylcarbonyl, carboxyl, C1-10 alkyloxycarbonyl, amino, mono- or disubstituted amino, aminocarbonyl, mono- or disubstituted aminocarbonyl, where the substituents of any of the amino groups are each selected in individual form of phenyl, C1-10 alkyl, C2-10 alkenyl, C3-7 cycloalkyl, pyrrolidinyl, piperidinyl, homopiperidinyl or piperazinyl optionally substituted with C1-10 alkyl. |
| priorityDate | 2004-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 291.