http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2302651-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a947c5b565bf9b9919794f03db37eca |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 2007-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf09914839a893dbd15acfb5837f4fbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_063ae1112a20c146395d817762b396c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b802e43779617abe0c364f20e909da5 |
publicationDate | 2008-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2302651-A1 |
titleOfInvention | PROCESS FOR PREPARATION OF MONTELUKAST AND PRECURSORS OF THE SAME. |
abstract | Process for preparation of montelukast andnprecursors of it.n n n The present invention provides a processnto stereoselectively reduce acid methyl estern2- [3- [3- [2- (7-Chloro-2-quinolinyl) -etenyl] phenyl] -3-oxopro-pil] benzoic,nin order to producen2- [3- (S) - [3- [2- (7-Chloro-2-quinolinyl) -etenyl] phenyl] -3-hydroxypropyl] benzoaten of methyl, and a process to produce montelukast or a salt ofnsame. The present invention further provides a processnto purifyn2- [3- (S) - [3- [2- (7-Chloro-2-quinolinyl) -etenyl] phenyl] -3-hydroxypropyl] benzoatenof methyl The reduction process of the present invention usesna chiral reagent and can provide the reduction productndesired with a high enantiomeric excess (ee). |
priorityDate | 2006-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.