http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2298049-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d904e68b6e0b4f6ce1d0cbcd02d8a99 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
filingDate | 2006-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e070eebf9ce2d8b94ae9dfefbda24e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce51bb87f91c72f95a621085bb1c1d2d |
publicationDate | 2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2298049-B1 |
titleOfInvention | PROCEDURE FOR MANUFACTURING BROMIDE OF 3 (R) - (2-HIDROXI-2,2-DITIEN-2-ILACETOXI) -1- (3-PHENOXIPROPIL) -1-AZONIABICICLO (2.2.2) OCTANO. |
abstract | Process for manufacturing 3 (R) - (2-hydroxy-2,2-dithien-2-ylacetoxy) -1- (3-phenoxypropyl) -1-azoniabicyclo bromide [2. 2.2] octane.n n n The invention consists of a process thatncomprises carrying out the quaternary reaction between thenestern1-Azabicyclo [2.2.2] Oct-3 (R) Ilicnof the acidn2-hydroxy-2,2-dithien-2-ylaceticnand 3-phenoxypropyl bromide in a solvent ornsolvent mixture that has a boiling point ofn50 to 210 ° C and which is selected from the group consisting ofnketones and cyclic ethers. The use of a single is preferrednsolventn n n The process of the present inventionnallows to reduce the reaction time and the amount ofnsolvents and alkylation reactants used thereinntime the performance is increased and the level ofnimpurities |
priorityDate | 2006-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.