http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2296530-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d12b35c0dd9adfb167b3b4f383afe93 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08 |
filingDate | 2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abd5560473137ae933bb43af2cfd3570 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eae777bcba7511ae6c29b8593f7b1cd7 |
publicationDate | 2008-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2296530-A1 |
titleOfInvention | LAUNCH COMPOUNDS THROUGH THE BARRERA HEMATOENCEFALICA AND CONSTRUCCIONES LANZADERA-CARGO. |
abstract | Shuttle compounds through the barriernblood brain and constructionsnshuttle-cargo.n n n The compounds of formula (I), where R 1 andnR 3 are H or (C 1 -C 4) alkyl; R2nis H or a C-radical derived from one of the systemsnknown ring 1-4 rings; X_ {1} is anbiradical (C 1 -C 8) -alkylnderived from a linear or branched carbon chain; and X_ {2} isn-NH-,n-NH- (CH2) 1-3 -COO-,n-NH- (CH2) 1-3 -S- orn-NH-CO- (CH2) 1-3 -S-,nthey are useful as shuttles across the blood brain barriern("blood brain barrier", BBB). BBB shuttle constructionsncharge are useful as medications, being the charge a substancencapable of forming an amide bond or an ester bond or a bondndisulfide with X2, and being unable to cross the barriernblood brain by itself. |
priorityDate | 2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.