| abstract |
Drug-free preparation of propellant gases, for inhalation application, composed of * a tiotropium salt as an active ingredient, in a concentration referred to tiotropium, between 0.0005 and 5% by weight, * only water or a mixture of water / Ethanol as solvent for the active substance, * acid to adjust a pH value between 2, 0 and 3, 1, * a pharmacologically tolerable preservative, * optionally, editinic acid or an editinic acid salt in an amount of more than 0 to 25 mg / ml, * optionally, a complexing agent and / or pharmacologically acceptable stabilizer and / or a pharmacologically acceptable co-solvent and / or other pharmacologically acceptable adjuvants and additives, in addition to the preservative. |