| abstract |
A compound of formula (I): in which: A is absent or is (CH2) 2; R1 is C (O) NR10R11, C (O) 2R12, NR13C (O) R14, NR15C (O) NR16R17, NR18C (O) 2R19, heterocyclyl, aryl or heteroaryl; R10, R13, R15, R16 and R18 are hydrogen or C1-6 alkyl; R11, R12, R14, R17 and R19 are C1-8 alkyl (optionally substituted with halo, hydroxy, C1-6 alkoxy, C1-6 haloalkoxy, C3-6 cycloalkyl (optionally substituted with halo), C5-6 cycloalkenyl, S ( C1-4 alkyl), S (O) (C1-4 alkyl), S (O) 2 (C1-4 alkyl), heteroaryl, aryl, heteroaryloxy or aryloxy), aryl, heteroaryl, C3-7 cycloalkyl (optionally substituted with halo or C1-4 alkyl), C4-7 cycloalkyl condensed with a phenyl, C5-7 cycloalkenyl or heterocyclyl ring (optionally substituted with oxo, C (O) (C1-6 alkyl), S (O) k (C1-6 alkyl), halo or C1-4 alkyl); or R11, R12, R14 and R17 can also be hydrogen; or R10 and R11, and / or R16 and R17 may be joined to form a 4, 5 or 6 membered ring that optionally includes a nitrogen, oxygen or sulfur atom, said ring being optionally substituted with C1-6 alkyl, S ( O) l (C1-6 alkyl) or C (O) (C1-6 alkyl); R2 is phenyl, heteroaryl or C3-7 cycloalkyl; or a pharmaceutically acceptable salt thereof or a solvate thereof. |