http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2291135-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa699e1bf6a93218e0d37c7f4e31468b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-412 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-54 |
| filingDate | 2006-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86fde3fa08c177da93d602e179dc4736 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37a86cbf58eb9582dea8d5ba68a3168f |
| publicationDate | 2008-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2291135-B1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF TARTRATE OF (R) -TOLTERODINE. |
| abstract | Procedure for the preparation of tartraten(R) -tolterodine comprising: reducing anbenzopyranone, of formula 1, with sodium borohydride to formna dialcohol, of formula 12; react the hydroxyl groups ofndialcohol with mesyl chloride to introduce two groups ofnmethanesulfonyl and form a dimesylated compound, of formula 13;nreact the dimesylated compound, with low diisopropylaminenpressure, and then with sodium hydroxide to getntolterodine isolating it as the corresponding hydrobromide, fromnformula 14; release tolterodine base from hydrobromide, andnthen react it with acidn(+) - tartaric to prepare tartraten(R) -tolterodine. |
| priorityDate | 2006-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.