http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2291120-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1e201480254114672f3d2f4daf1f231 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2006-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ea0d1c29afe2dfb501c00f48df7515f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f5ed95767c668e818e02add0db3367a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_368e7c8cdfdec80391385989cbbf587e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6e0543da294cf2f484a651ef622b007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f36e66342ed09881f915e7cf3158603b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a7e2e34a5fd4421a2cab1c53a89b419 |
publicationDate | 2008-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2291120-A1 |
titleOfInvention | SYNTHESIS AND USE OF THE CU-FENANTROLINA-IODOHIPURIC ACID COMPLEX AND RELATED COMPOUNDS AS ANTITUMORAL PHARMACOS. |
abstract | Synthesis and use of the Cu-fenantroli- ternary complex iodohipuric acid na-and related compounds as antitumor drugs.n n n The present invention relates to complexesnternaries formed by Cu (II),n1,10-phenanthroline or 2,2-bipyridylnand different hippuric acids of general formula (I):n n \ vskip1.000000 \ baselineskipn n n \hskip2cm [Cu\nA\ B_{2}]^{+}C\cdot nH_{2}O \hskip2cm n(I) \ hskip2cm [Cu \ A \ B_ {2}] + C \ cdot nH_ {O} \ hskip2cm (I)n n \ vskip1.000000 \ baselineskipn n n where A is selected from:nI-hip, Hip, BGG and BI GG; B is selected fromnBetween: phen and bpy; C is selected fromnI-hip <->, Hip <->, B <1> GG <->, BGG <-> andnI <->; and n, if it exists, are the crystallization waters that cannvary between 1 and 7. These compounds in solution have anhigh stability in the form of Cu (I) complexes, which actnat the DNA level and, therefore, are useful as antitumor agents,nparticularly in human cancer and especially cancer ofnlung. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2407164-A1 |
priorityDate | 2006-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.