http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2287731-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c111b0bf5b8826bb4f69ae577a82bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acce10094053864f06ba94d7bf464f66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7f2e3f9d09df55457cc2948d8dabffc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e2442bb60f497e2e6f8a5542f0e48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2004-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72bd8da7307006baed61a1bb3d0185cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c62bb861b8e015229cbc74ffa9a42ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_727fa31a016429ae4091c369622bab01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe866a63f40037ceb6d4e71539e42dff |
| publicationDate | 2007-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2287731-T3 |
| titleOfInvention | ECRUTINY FOR NEW PROTEIN INHIBITORS BASED ON A CELLULAR LINE OBTAINED BY GENETIC ENGINEERING THAT CONTAINS AN INDUCIBLE OVERACTIVITY GENE AND A COMPENSATORY GEN. |
| abstract | A method for identifying the presence of an inhibitor of a target protein in a sample, comprising the steps of: a) contacting said sample with a cell, wherein said cell contains (i) a mutation of inducible lethal overactivity in a gene that affects the target protein, where the activity of the target protein is essential for the cell; and (ii) a mutation in a second gene, wherein the mutation in the second gene functionally compensates for any reduction in the activity of the target protein; b) induce the lethal overactivity mutation; and subsequently c) determine the inhibition of the protein by comparing the degree of cell survival in the presence and absence of said sample. |
| priorityDate | 2003-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.