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filingDate 2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff245e7dc72b36741f2d4183656e6f27
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publicationDate 2007-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2280226-T3
titleOfInvention MORPHINE SULFATE MICROGRANULES, PREPARATION AND COMPOSITION PROCEDURE CONTAINING THEM.
abstract Prolonged morphine sulfate microgranules each comprising a neutral support grain coated by an active layer and by a prolonged-release layer, characterized in that the prolonged-release layer contains a copolymer of methacrylic acid and methyl methacrylate ester whose relative proportion of free carboxyl groups and ester groups is equal to approximately 0.5, and a silica having a hydrophobic character.
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