http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2271660-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42b66fd6ac8d432f925152eef843ebe7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5355 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 |
| filingDate | 2003-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f0a4147726eb080835389ba8c01d26c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df2c9cde5f437c904e93c10155d78e0d |
| publicationDate | 2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2271660-T3 |
| titleOfInvention | DERIVATIVES OF N- (4-PIPERAZIN-1-IL) -FENIL-2-OXAZOLIDINONA-5-CARBOXAMIDE AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS. |
| abstract | A compound of formula I or its pharmaceutically acceptable salts, in which: A is a structure i, ii, iii or iv; B is W is -N (H) C (X) -R1, Het or -Y-HET, in which Het or -Y-HET is optionally substituted with = S or = O, with the proviso that when A is structure iv, W is not -Y-HET or Het; X is O or S; Y is NH, O or S; Z is R1 is a) H, b) NH2, c) NH (C1-4 alkyl), d) C1-4 alkyl, e) C2-4 alkenyl, f) O- (C1-4 alkyl), g) S - (C1-4 alkyl), oh) (CH2) 8 (C3-6 cycloalkyl), where each time alkyl or cycloalkyl appears in R1 is optionally substituted with one, two or three halogens (F or Cl); each R2 and R3 is independently hydrogen, halogen (F or Cl), methyl or ethyl; R4 is H, CH3 or F; R5 is H or C1-4 alkyl; R6 is H, C1-4alkyl or R5 and R6 together form an optionally substituted saturated heterocycle; R7 is H, or C1-4 alkyl which may be optionally substituted with -OH, -NH2, -NH-C (= NH) -NH2, -SH, -SCH3, -COOH, -C (O) NH2, phenyl which it may be optionally substituted with -OH; R8 is H or CH3; R9 is H, CH3, -C (O) -CH (R7) -NR8R8, R10 or R11 is halogen, C1-4 alkyl, CF3, -CN, -NO2, -OH, -O-C1-4 alkyl, - NH-S (O) w (C1-4 alkyl); R12 is H, C1-4 alkyl, -S (O) 2-C1-4 alkyl, or R5 and R12 together form a saturated heterocycle; R13 is H, or R14 is - (CH2) tNHR13, -OH, -O (C1-4 alkyl); m is 0, 1, 2, 3, 4; n is 0, 1, 2, 3, 4, with the proviso that m plus n is 2, 3, 4 or 5; p is 2, 3; q is 1, 2; r, s and t are independently 0, 1; u and w are independently 0, 1, 2; and with the proviso that W is not Het or -Y-HET when Z is a, b or d, and with the condition that Z is not b when A has the formula iii. |
| priorityDate | 2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 268.