| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20023 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate |
2000-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd3e26b67b7641bd057effaf46c1011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef6f0795061405c5c3c68f643a0f3bcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dd732b61df2587dd210076f4f5ad499 |
| publicationDate |
2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2270822-T3 |
| titleOfInvention |
PROCEDURE FOR PREPARING A HUMAN PAPILOMAVIRUS VACCINE WITH DISASSEMBLED AND REASSEMBLED VIRUS ANALOG PARTICLES. |
| abstract |
A process for making a human papillomavirus vaccine comprising particles analogous to the HPV virus (VLPs), the method comprising the steps of: (a) incubating VLPs in a dissociation mixture comprising 2-20 mM dithiothreitol (DTT), a salt present in a NaCl equivalent range of 0.10M to 0.2M, a non-ionic surfactant, a metal chelating agent, and a buffer until disassembly of the VLPs occurs; (b) remove the reducing agent from the dissociation mixture; and (c) reassemble the disassembled VLPs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110987571-A |
| priorityDate |
1999-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |