abstract |
A pharmaceutical oral dosage form of ultrafast fusion that will disintegrate in the mouth in less than about 25 seconds, comprising a medicament and a combination of excipients comprising, based on the total weight of the dosage form, a) between 4 and 8% by weight of a superdisintegrant, b) between 20 and 70% by weight of a disintegrating agent that is calcium silicate c) between 1 and 10% by weight of a distribution agent selected from amorphous silica, pyrolysis silica, earth of diatoms, talc, kaolin and magnesium aluminum trisilicate, and d) between 10 and 50% by weight of a binder. |