| abstract |
A compound, or its possible salt, which has the formula 1. where: Re and '' Re are OH, optionally independently etherified or esterified; Z is -C (R4, R5) - where R4 and R5 are independently alkyl (1C-2C) or together form a spirocycloalkyl (3C-5C): R1 is H, halogen, CF3, or (1C-4C) alkyl; R2 and R3 are, independently, H, halogen, -CF3, OCF3. (1C-8C) alkyl, hydroxy, (1C-8C) alkyloxy, aryloxy, arylalkyl ((1C-8C), haloalkyl (1C-8C), -O (CH2) mX, where X is halogen or phenyl and m = 2- 4; -O (CH2) mNRaRb, -S (CH2) mNRaRb or (CH2) mNRaRb, where m = 2-4 and where Ra, Rb are independently alkyl (1C-8C), alkenyl (2C-8C), (2C-8C) alkynyl, or aryl, the alkyl, alkenyl and aryl may be optionally substituted with halogen, -CF3, OCF3, -CN, -NO2, -OH, alkoxy (1C-8C), aryloxy, carboxyl, alkylthio ( 1C-8C), carboxylate, (1C-8C) alkyl, aryl, arylalkyl (1C-8C), or haloalkyl (1C-8C); or Ra and Rb form a 3-8 link ring structure, optionally substituted with halogen, - CF3, OCF3, -CN, -NO2, hydroxy, hydroxyalkyl (1C-4C), alkoxy (1C-8C), aryloxy, alkylthio (1C-8C), carboxyl, carboxylate, alkyl (1C-8C), aryl. Arylalkyl - (1C-8C), haloalkyl (1C-8C). |