| abstract |
Compounds of the general formula 1, (See formula) in which R1 means hydrogen, hydroxy, CF3, NO2, CN, halogen, C1-C8 alkyl or C1-C8 alkoxy; R2, R3 and R4 independently of each other, mean hydrogen, C1-C8 alkyl, hydroxy, NO2, CN, C1C8 alkyloxy, CF3 or halogen; R5 and R6 independently of each other, mean hydrogen or a radical selected from the group consisting of C1-C8 alkyl, C2-C8 alkenyl, C3-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-C1-C8 alkylene , C5-C8 cycloalkenyl, C5-C8 cycloalkenyl-C1-C6 alkylene, C6-C10 aryl and C6-C10 aryl-C1-C6 alkylene, which may eventually be substituted with a radical selected from the group consisting of C1-C6 alkyl , C2-C6 alkenyl, halogen, C1-C6 alkyloxy, -NH2, -NH (C1-C4 alkyl), -N (C1-C4 alkyl) 2, hydroxy, = O, -COOH, -CO-O-C1-alkyl -C4, -CONH2, -CONH (C1-C4 alkyl), -CON (C1-C4 alkyl) 2 and CF3, or R5 and R6 in common with the nitrogen atom, mean a saturated or unsaturated heterocycle of 5, 6, 7 or 8 members, which eventually contains one or two additional heteroatoms selected from sulfur, oxygen and nitrogen, and may eventually be substituted once, twice or three times with a radical selected from C1-C4 alkyl, hydroxy, = O, -COOH , - CO-O-C1-C4 alkyl, -CONH2, -CONH (C1-C4 alkyl), -CON (C1C4 alkyl) 2, halogen and benzyl; X means oxygen, -NH-, -N (CHO) -, -N (CO-C1-C6 alkyl) -, -N (C1-C6 alkyl) - or -N (C3-C6 cycloalkyl-C1-C4 alkylene) , preferably oxygen or -NH-; A means a radical selected from C1-C6 alkylene, C2-C6 alkenylene and C3-C6 alkynylene, which may eventually be substituted with a radical selected from halogen, = O and hydroxy. |