abstract |
A compound comprising the general formula: wherein G1 is selected from the groups a and b: A is selected from the group phenyl, pyridinyl, pyrimidinyl and thienyl, all optionally substituted with C1-C6 alkyl, halogen, halogenoalkyl, alkoxy, cyano, nitro , -SO2R¿, -NSO2R¿, -SO2NR¿R¿, -NR¿R¿ or ¿COR¿; R¿ and R¿ are each independently hydrogen or C1-C6 alkyl; G2 is selected from the group represented by formulas c, d, e, f, g, h, i and j: R1 and R2 are independently selected in each case from the group consisting of hydrogen, C1-C6 alkyl, halogen, halogenoalkyl, nitro, -NR¿R¿, -OR¿, -SO2R¿, -NSO2R¿, -COR¿, cyano, nitro, phenyl optionally substituted with halogen, alkyl, cyano or alkoxy; or heteroaryl optionally substituted with halogen, alkyl, cyano, or alkoxy; or R1 and R2 if adjacent, taken together with the carbons to which they are attached, can also form an aromatic ring, optionally substituted with one or more substituents selected from lower alkyl, halogen, cyano, or lower alkoxy, or individual isomers, mixtures racemic or non-racemic isomers, prodrugs or solvates or pharmaceutically acceptable salts thereof. |