| abstract |
Procedure for the preparation of inhalation powders, characterized in that N + m portions of approximately equal size of a substance with a larger distribution of the particle size, which represents the adjuvant, and N portions of equal size of a substance with a smaller distribution of the substance Particle size, which represents the active substance, is intermittently added in layers to a suitable mixing vessel and, after complete addition, the 2N + m layers of the two components are mixed by means of a suitable mixer, with the first adding a portion of the substance with a larger particle size, N being an integer> 0, preferably> 5, and m representing the number 0 or 1. |