abstract |
Compound of formula (I): (See formula) represents a 5-link nitrogen heterocycle optionally substituted with a cyano group, represents a hydrogen atom or a linear or branched (C1-C6) alkyl group, linear (C1-C6) acyl or branched, prolyl, alanyl, histidylprolyl or phenylalanylprolyl, - Ak represents a linear or branched (C1-C6) alkylene chain or heteroalkylene, - X represents a single bond or a phenylene group optionally substituted with one or more identical or different groups, selected from halogen atoms and linear or branched (C1-C6) alkyl, hydroxyl, linear or branched (C1-C6) alkoxy or linear or branched (C1-C6) polyhaloalkyl groups, - R2 represents a (C3-C10) cycloalkyl group , - Y represents an NH group, its optical isomers and its addition salts of a pharmaceutically acceptable acid, it being understood that a 5-link nitrogenous heterocycle means a saturated 5-link monocyclic group containing one, two or three heteroatoms, one of these heteroatoms being a nitrogen atom, and the supplementary heteroatom or atoms optionally present among oxygen, nitrogen or sulfur atoms, and heteroalkylene chain is understood to mean a linear (C1-C6) alkylene chain or branched in which a link -CH2 has been replaced by an oxygen or sulfur atom. |